Because its a very good place to place a device which knows what the temperature of the air being experienced by the occupants is?
We have like most houses rooms with doors, and the radiators in each room naturally circulates air,
so good place to monitor air temperature is the air returning to radiator, be it a fan assisted like a Myson or conventional with a TRV added, specially when the TRV has two sensors one which compensates for water temperature.
There is in theory nothing to stop one having a wall thermostat in every room, all wired in parallel, and a TRV in every room, the wall thermostat ensures the boiler runs when required, and the TRV stops any room over heating. However in practice I am sure one would find some rooms don't need a wall thermostat as the boiler would be running anyway. So in real terms likely more than one room with wall thermostat but not every room, and we know there are wall thermostats designed to run and master/slave configuration, so can even do that with OpenTherm.
My last house was designed open plan, and one thermostat between the living and dinning room next to archway could control the whole house, with some TRV's upstairs to stop bedrooms over heating if doors left open, not needed if bedroom doors kept closed, so yes a house can be controlled with one thermostat, but most houses do have doors, and the old idea was a thermostat in a room kept cool, so thermostat can be set low, so will not run central heating on warm days, on the ground floor as heat raises, with no outside doors, or alternative heating, but the problem is often such a room does not exist.
So we hunt for a compromise, and the more adaptable the thermostat/hub is the more homes it can be successfully used in, but we can control heating rates (lock shield valve) and stop over heating (basic TRV) but we can't control cooling rates. Also we tend to use rooms as certain times of the day, for example bedrooms at night and living room in the day, so we have all these programmable TRV heads so rooms only heated when required, then try to control the boiler with a single non linked thermostat, and it does not take rocket science to see the flaw.
My hall connects to 4 rooms, and is on the ground floor well OK middle floor but we don't use rooms under main house, but where the wall thermostat is could not really be more central, and it is affected by all the adjoining rooms, so would seem the ideal place, but the hall cools too slowly. Outside door in hall never used, so it ticks all the boxes, except it cools too slowly.
And in all but that open plan house, I have had a problem with the thermostat not turning on the boiler when required, be it sun in a bay window, wind direction, alternative heating like gas fires, only the open plan worked, we would come home, turn the thermostat up, switch on the 4.5 kW gas fire, and the main room was toasty warm within 15 minutes and we would within 30 minutes hear the Myson fan assisted radiator turn off. The house was designed to be heated by that single gas fire, but the gas fire was not thermostatic controlled, so as soon as warm would turn it off, and central heating maintained the heat in the house. No need for geofencing, or other clever thermostats, it was simply down to house design, but was a draw back, could not stop sound travelling, so not a perfect house.
However when I lived there I could not understand why anyone had a problem, it worked, only when I went to a house with doors did I realise there was a problem with some homes. The home before that one used gas hot air heating, and there were vents in every door for air to return to boiler, well suppose not a boiler when no water to boil, expensive to run, but again one thermostat controlled all.
So there is no one heating system suits all, but it is very limited as to which homes can be controlled with a single thermostat.
Oh and the open window on eQ-3 can be configured to what you want, it does not have to be used.