So if you put an inline fan halfway along the duct, are you effectively able to use more duct length with it than you would be able to if you put the same fan at (or near) one end?That’s not so bad. Flexi slows down air flow because of the ridges inside flexi-duct.
A powerful in-line fan may be a good solution (if you have space under the floor!). You'll get much better performance on that long duct length with one of these if you position the fan half way along the duct.