Practical experience can get you through most of the time, but occasionally theoretical understanding may be necessary.
For example, I was checking how much of the F&E pipe could get hot and I estimated that, for an average system, one degree increase in average water temperature should cause a movement of around 150 mm in the F&E (assuming none goes up the vent). So I should not be alarmed at an F&E pipe that is hot for several metres.
I read that the vent pipe should be a maximum of 150 mm away from the F&E pipe - but I could not find out why. This must be related to my original question. To know why this dimension is given would be necessary if, for example, there were constraints on pipe runs.