The Opentherm module in the 3 channel only triggers the boiler if there is demand on heating channel 1, it ignores demand on heating channel 2. I also don't know for certain that the module is actually sending Opentherm signals to the boiler...it may just be closing the circuit.
The optimisation on the Wiser is pretty good.
@floob Your half and half idea of control won't work. Consider- you have your sitting room with WiFi rad valves, dining room with ordinary trv. You want sitting room warm- fine, valves set to temp and call for heat. The dining room is going to heat on the same schedule as the sitting room.
Only by going full controllable heads can you have an individual schedule (temperature and time) for individual rooms.
You also have to watch system efficiency- if only 1 rad is calling for heat and that rad is quite small (below the bottom range of your boilers modulation capability) then you may get into boiler cycling.
From a comfort pov, you may find that you want to leave the hallway (and bathroom) rads on conventional TRVs rather than smart ones to keep some background heat in those spaces- also avoids cycling and low efficiency probs as above.